THERAPEUTIC AREAS
Hidradenitis Suppurativa
Hidradenitis suppurativa needs new treatment
Hidradenitis suppurativa or HS, is the first inflammatory disorder we are working to alleviate for patients through our pipeline.
What is HS?
HS is a chronic inflammatory skin condition that causes painful lumps, abscesses, and scarring to develop in areas where skin often rubs together like armpits, groin and under the breasts. When hair follicles become blocked, inflammation can begin and lead to deep, painful nodules that eventually rupture and drain fluid.
People with HS often experience symptom flare-ups that can significantly impact daily activities and their quality of life.
Why are new treatments needed?
Only 3 in 10 people achieve meaningful symptom relief and clinical improvement with current treatment options.*
Current biologic treatments can be less effective for some people due to differences in how medications are absorbed and distributed in the body. In larger people living with HS this can mean the medications do not always work as intended.
Today, in the absence of effective treatment many patients experience delayed diagnosis and only 350,000 currently seek treatment, with many people struggling to manage their symptoms for years.
The visible nature of the condition and its impact on intimate areas can profoundly affect self-esteem, relationships, and overall mental health, underscoring the critical need for effective new options.
Over one million people in the U.S. live with moderate-to-severe HS which affects three times more women than men.
Where can I find out more?
If you or a family member are living with HS, the following U.S. organizations can provide information and support:
*Clinical improvement defined as the Hidradenitis Suppurativa Clinical Response 75 (HiSCR75) which included a 75% or more reduction in inflammatory nodules or abscesses and no increase in abscesses or draining tunnels.